ABSTRACT
Introduction: Breast cancer in Nigerian and
African women is characterized by young age at presentation. They present
approximately a decade earlier than patients in western countries.
Objective:
The aim of the study is to evaluate the demographic and histopathological
features of pre- menopausal women with locally advanced breast cancer.
Methodology: All premenopausal patients who
presented with histologically confirmed locally advanced breast cancer were
counseled and recruited into the study. The patients were evaluated
demographically and clinically. The data were analyzed using the SPSS
statistical software version 23.0 (Statistical Package for Social Sciences SPSS
Inc.) 2015.
Results: A total of 49 patients had
confirmation of breast carcinoma via core needle biopsy of their breast
lesions. The age of the study population ranged from 24 - 54 (40.92±7.98)
years. The majority of the patients, 41 (83.7%) out of 49, gained secondary education.
All had primary education. Only 6 (12.2%) of the patients were nulliparous.
Thirty (61.2%) had parities of 4 and above.
Invasive
ductal carcinoma was confirmed in 45 (91.8%) of the patients. The duration of
breast lump before presentation ranged from 1-36 months with a mean duration of
10.02±8 months.
The size
of the breast masses ranged from 3.0-25.0cm with a mean of 9.70±4.33cm. The
size of the breast masses and the duration showed a positive correlation,
Pearson's correlation +0.575(0.00).
Conclusion: There is a 100% literacy level
among the patients in our study population yet there is still a general delay
in hospital presentation. The invasive ductal carcinoma is the predominant
histological type of breast cancer in our centre.
Key words: Premenopausal breast cancer,
Histology, Demography, Features.